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Synthroid - 20 Drug Reviews & Ratings - DrugRatingz.com Category: hormone therapy weight gain and fluid retention. Endocrinologist took me off Armour and prescribed synthroid and cytomel instead. Says he'll take me off cytomel on next visit. I want my ARMOUR back!!! When my endo switched me to Synthroid from my Armour Thyroid/Cytomel combination, it was a disaster. I gained 12 pounds (which I'm still trying to lose) in addition to weight I'd gained before being diagnosed and my face was so swollen it looked like someone had beaten me up (family attested to this). Also my joints ached and I had no energy. Synthroid may work fine if you have what I'd call simple hypothyroidism (i.e., low thyroid not complicated by other hormonal issues), but many, many people seem to do better on Armour, sometimes with Cytomel. You should always have ALL your major hormones (thyroid, cortisol, estrogen, progesterone, testosterone, etc.)tested if the med isn't working, IMO. Supposedly the most accurate way to do it is by saliva testing.

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